Application of thin film microfluidic pouch in respiratory infection pathogen detection
Publish Time: 2025-07-14
With the increase of global public health challenges, it is particularly important to diagnose respiratory infection pathogens quickly and accurately. Especially during the flu season or when facing an outbreak, the ability to quickly identify specific pathogens is crucial for timely and effective treatment measures. As an advanced technical means, thin film microfluidic pouch plays a key role in the AE series nucleic acid detection all-in-one machine, especially for the detection of respiratory infection pathogens.
1. The basis and principle of thin film microfluidic pouch
Thin film microfluidic pouch is an integrated and portable sample processing and analysis platform. It uses microfluidic technology to reduce complex biochemical reactions to a miniaturized system. This design not only reduces the amount of reagents, but also speeds up the reaction and improves the detection accuracy. In the detection of respiratory infection pathogens, thin film microfluidic pouch combines nucleic acid extraction, amplification and detection functions in one, and the entire process can be completed through simple operation steps.
2. Efficient and accurate detection capability
The thin film microfluidic pouch that comes with the AE series nucleic acid detection all-in-one machine is optimized for common pathogens of respiratory tract infections. These pathogens include but are not limited to influenza viruses (such as H1N1), coronaviruses (such as SARS-CoV-2), adenoviruses, etc. The high-sensitivity detection module built into the thin film microfluidic pouch can effectively capture the target nucleic acid sequence from patient samples and amplify and quantify it through real-time fluorescence quantitative PCR or other molecular biological methods. This process greatly shortens the time required for traditional laboratory testing, and results can usually be obtained within 30 minutes to several hours.
3. Multi-scenario adaptability
The design of the thin film microfluidic pouch takes into account the needs of different medical environments, and it can be easily used in wards, emergency departments, or primary medical institutions. Its lightweight and portable features make it very suitable for point-of-care testing (POCT), without the need for complex equipment support or professional technicians to operate. This is particularly valuable for areas with limited resources because it can provide diagnostic information at the first time, guide clinical decisions, and avoid disease delays.
4. Simplify the operation process
Traditional pathogen detection often requires multiple steps, including sample collection, transportation, pretreatment and final laboratory analysis, which is not only time-consuming and laborious, but also increases the risk of cross-contamination. In contrast, the thin film microfluidic pouch greatly simplifies this process. Users only need to follow the instructions, add the collected samples to the thin film microfluidic pouch, and then insert it into the AE series nucleic acid detection all-in-one machine to automatically complete all subsequent steps. This one-button operation mode greatly reduces the possibility of human error and improves the consistency and reliability of detection.
5. Promote the development of personalized medicine
In addition to its important role in the prevention and control of acute infectious diseases, the thin film microfluidic pouch also provides the possibility of personalized medicine. By accurately identifying the respiratory pathogens of individual patients, doctors can formulate personalized treatment plans according to the specific situation, choose the most appropriate drugs, reduce unnecessary use of antibiotics, and thus reduce the risk of drug resistance. In addition, long-term monitoring of the changing trends of pathogens in patients can also help to better understand the development of the disease and provide a scientific basis for prevention and control strategies.
In conclusion, as an important component of the AE series of nucleic acid detection all-in-one machines, the thin film microfluidic pouch has shown great potential in the detection of pathogens of respiratory infections. It not only improves the efficiency and accuracy of detection, but also significantly improves the accessibility and quality of medical services, providing strong technical support for coping with current and future health challenges.
